This large single center cohort found several factors associated with the risk of non-ICU GI bleeding; researchers developed a scoring system to determine which patients were at highest risk of bleeding (and presumably would benefit from GI prophylaxis). The following factors were included (including their score): age >60 (2), male (2), acute renal failure, (2) liver disease (2), sepsis (2), VTE prophylaxis (2), coagulopathy (3), medical service (3). Those at highest risk (score 12+) had a GI bleed in 3.2% of those not on GI prophylaxis, and 1.1% of those on GI prophylaxis. This helps define those non-ICU hospitalized patients that would benefit from GI prophylaxis (abstract).
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