ACE inhibitor small bowel angioedema

This case series describes 20 patients presenting to the ED with acute abdominal pain, found to have small bowel angioedema on imaging, and were all on ACE inhibitors (mean duration 3.3 years). Several cases were preceded by a dose increase, and resolved after stopping the drug. Although not definitively causal, it is biologically plausible and may need to be considered in patients on ACE inhibitors with acute abdominal pain and evidence of localized bowel edema. (abstract)

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