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Category Archives: Neurology
No steroids for acute spinal cord injury
New consensus guidelines do not recommend steroids for acute spinal cord injury, citing studies that they do more harm than good (including higher rates of infections, complications, ICU LOS, and death) (abstract).
Posted in Neurology
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Survival after discharge after in-hospital cardiac arrest
This large cohort of patients age>65 who survived in-hospital cardiac arrest found that 1 year after discharge, 59% were still alive, and 34% had not been readmitted to the hospital. Both mortality and readmission rates were substantially affected by the … Continue reading
Posted in Neurology, Pulmonary and Critical Care
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Head CT not helpful for acute dizziness
This single center retrospective cohort of patients presenting to an ED with acute dizziness found head CT imaging to be diagnostic in only 2% of patients; MRI yielded a diagnosis in 16% of patients. This study supports the recommendations of … Continue reading
Posted in Neurology
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Quetiapine effective and relatively safe for delirium
This systematic review found quetiapine was more effective than placebo and as effective as haloperidol in reducing the duration of delirium, and is associated with fewer extrapyramidal side effects than the first generation antipsychotics. Quetiapine is a reasonable first line … Continue reading
Posted in Neurology
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Effect of delirium in critically ill
This meta-analysis of critically ill patients found significantly worse outcomes in those that experience delirium compared to those that do not, including higher mortality, more complications, longer vent duration, and longer ICU and hospital LOS (abstract). Continued efforts for prevention … Continue reading
Posted in Neurology, Pulmonary and Critical Care
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Acute stroke guidelines updated
A brief outline of the AHA/ASA guidelines can be found here (synopsis).
Posted in Neurology
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Endovascular treatment for acute stroke
In this randomized trial of patients with acute stroke s/p t-PA, they were randomized to further endovascular treatment or no treatment; the trial was stopped early, as the 90 day Rankin and NIHSS scores were no different between the groups, … Continue reading
Posted in Neurology
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Stroke guidelines updated
The AHA/ASA has updated their guidelines for the management of acute stroke; they stress the need for early thrombolytics, early transfer to a stroke center or use of telemedicine consultation when feasible. The full guidelines are at (AHA/ASA)
Posted in Neurology
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SSRIs post-stroke
This large meta-analysis of 52 trials found that SSRIs significantly reduced the risk of neurological deficit, dependence, disability, depression, and anxiety post stroke, compared to controls (abstract).
Posted in Neurology
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Trends in in-hospital cardiac arrest
In this analysis from 2000-2009 from the Get with the Guidelines registry of patients with in-hospital cardiac arrest, 80% had asystole or PEA, and 20% Vfib/Vtach. Survival to discharge increased from 14% to 22% over the time period. Neurological disability … Continue reading
Posted in Cardiology, Neurology
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