Category Archives: Cardiology
This meta-analysis of 12 studies of out-of-hospital cardiac arrest found that machine-delivered CPR was associated with ~1.5 times the odds of return of spontaneous circulation compared to human CPR. This may also be true for in-hospital arrest but needs further … Continue reading
In this trial of patients on warfarin undergoing a pacer/ICD procedure, they were randomized to continue warfarin perioperatively, or receive heparin bridge therapy. The study was stopped early when the heparin group suffered 4 times more device pocket hematomas than … Continue reading
This large randomized trial found lower mortality with CABG (vs PCI) in patients with diabetes, heart failure, peripheral arterial disease, or tobacco use; but those with none of these risk factors had lower mortality with PCI (abstract).
This large retrospective analysis of VA medical centers found that patients who received perioperative beta blockers (for noncardiac surgery) had significantly lower 30 day mortality if their revised cardiac risk index was 2 or higher. This study adds more evidence … Continue reading
This online risk calculator can help clinicians weigh the risks and benefits of ASA for individual patients (calculator).
In this large cohort of hospitals, researchers assessed the association between management practices (standardizing care, tracking key performance indicators, setting targets, and incentivizing employees) and process and outcome measures in patients with AMI. They found a significant correlation between high … Continue reading
This randomized trial found in patients with Stage 2-3 diastolic dysfunction, spironolactone improved diastolic dysfunction, but had no effect on symptoms, exercise capacity, or quality of life; and it was associated higher potassium levels and lower GFR. The current weight … Continue reading
This meta-analysis found that mild therapeutic hypothermia after cardiac arrest is both safe and effective and should be standard practice (abstract).
This large meta-analysis found a significant mortality benefit for all beta blockers in patients with systolic CHF, with no significant differences between the different types, indicating any beta blocker will do (abstract).
This small retrospective single center cohort found that 22% of patients on combination fluoroquinolone-azole drugs had clinically significant prolongation of their QT interval. Careful monitoring should be done for patients on this combination of drugs (abstract).